Portions of the following information were taken from Florida Geological Survey Bulletin 66.
Lafayette Blue Spring is located 7 miles northwest of Mayo on the west side of the Suwannee River. From the intersection of US 27 and SR 51 in Mayo, drive northwest on US 27 for 4.9 miles. Turn north (right) on CR 251B and continue for 2.1 miles on a gravel road. Turn east (right) onto a dirt road and go 0.2 miles to the county park entrance. Spring vent is east of the parking area in the pool farthest from the river.
Description – Lafayette Blue Spring discharges from a single horizontal vent in the south side of the sink depression. The spring pool measures 57 ft north to south and 102 ft east to west. Spring depth measures 21 ft. The water is clear and light bluish green. Algae are very thick on limestone and sand substrates within the spring pool and run. The spring run flows east approximately 300 ft before reaching the Suwannee River. Clear water from the spring contrasts sharply with the tannin-colored water of the river. Limestone is cropped out throughout the spring pool and run. A 20 ft wide land bridge stretches north to south across the spring run approximately 120 ft east of the vent. There is a narrow band of a few cypress trees near spring run. The spring pool is steep sided with limestone and sand. Adjacent high ground is approximately 20 ft above the water level, and it is sparsely forested with a few pines and oaks. Several sinks and karst windows are present in the woods west of the main spring.caveatlas.com/systems/system.asp?ID=47&rated=false#&tab=3